Alkyne Cross-Coupling Paper – In Press in J. Am. Chem. Soc.

The final, peer-reviewed version of our study in collaboration with the process chemistry team at Boehringer-Ingelheim on alkyne cross-coupling to access 1,3-enynes appears this week in J. Am. Chem. Soc. The high regio- and stereoselectivity of this reaction stems from the use of a hindered P,N-ligand previously developed at BI, which Mingyu and the BI team identified during his summer internship in Ridgefield, CT. Hats off to the entire project team: Mingyu, Tianhua (Josh), Omar, and Rei from Scripps Research; and Carl, Bo, Dan, Olga, Chris, and Jinhua (Jeff) from BI. Not a bad way to follow up your successful thesis defense from last week, Dr. Liu!

For a link to the paper, click here:

This work first appeared as a pre-print back in October: