Controlled Hydrochlorination of Alkynes with HCl

In the Engle lab’s first paper of 2017, the team of Joe, Annabelle, Mark, Miriam, Josh, Zhen, and Daizy describe a new catalytic method to effect regio- and stereoselective addition of HCl to alkynes using a directed nucleopalladation strategy. The paper appears today in the Just Accepted section of J. Am. Chem. Soc. Well done, everyone! Special congrats to the three undergraduate co-authors, Annabelle, Mark, and Josh, as well as Daizy, the Engle lab’s first-ever high school student co-author! Click here for a link to the paper.

IMG_2378(not pictured: Annabelle, Josh, and Daizy)