Appearing this week in Accounts of Chemical Research, we chronicle our lab’s journey developing air- stable nickel(0) precatalysts through organometallic investigations of electron-deficient diene (EDD) ligands. This long-standing collaboration between our lab and chemists at Bristol Myers Squibb has yielded several commercially available precatalysts that are widely used in industry and academia. Congrats to the authors, Camille, Wen-Ji, and Steve (from BMS), and thanks to all of the coworkers over the years whose contributions are featured in this article.

For a link to the article, click here: https://pubs.acs.org/doi/10.1021/acs.accounts.3c00638

Today, our collaborative study with the Baran lab and colleagues from Bristol Myers Squibb, Biogen, Leo Pharma, and Enamine describing a new nickel/electrocatalytic decarboxylative arylation method to access quaternary centers appeared online in Angewandte Chemie, International Edition. The method uses a unique combination of pyridine and BINAP as ligands to enable an otherwise challenging coupling event. Camille from our lab contributed to elucidating the complex mechanism of this process. We had a blast collaborating with the team on this creative and useful method!

For a link to the paper in Angewandte Chemie, International Edition, click here: https://onlinelibrary.wiley.com/doi/10.1002/anie.202314617

As a reminder, a ChemRxiv pre-print on this work was uploaded in September 2023: https://chemrxiv.org/engage/chemrxiv/article-details/64f248dddd1a73847ffb6e0d