1,2-Dicarbofunctionalization of Unactivated Alkenes

In a manuscript that appears in today’s online version of J. Am. Chem Soc., Zhen, Tian (May), and Kin describe a new method to carry out β,γ-vicinal dicarbofunctionalization of 3-butenoic acid derivatives using a directed nucleopalladation strategy. Of special note, May becomes the first undergraduate student to co-author a paper in the Engle group. Way to go, team! Click here for a link to the paper.web

img_4494(not pictured: Kin)

“Homo-Michael” Addition to Alkenes

Congratulations to Kin, John, and Zhen on the group’s newest paper, “Catalytic, Regioselective Hydrocarbofunctionalization of Unactivated Alkenes with Diverse C–H Nucleophiles,” which appeared online today in  J. Am. Chem. Soc. This reaction accomplishes a “homo-Michael” γ-selective addition of carbon-based nucleophiles to alkenyl carbonyl compounds. Click here for a link to the article.

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