As part of the Organometallic Solutions to Challenges in Cross-Coupling special issue in Organometallics, our lab reports an usual rearrangement process triggered by addition of Pd(TFA)2 to alkenes containing a benzothiazole thioether (BT(S)) directing group. The transformations furnishes a structurally family of previously unknown tetrahydrothiophene-functionalized N,S-heterocyclic carbene palladium(II) complexes that are catalytically active in various C–C coupling reactions. Congrats to grad student Andrew, former high school intern Matt, as well as our treasured X-ray crystallography collaborators Milan and Arnie from UCSD.
For a link to the accepted manuscript, click here: https://pubs.acs.org/doi/10.1021/acs.organomet.1c00041
The work first appeared on ChemRxiv back in January. Check out the pre-print here: https://chemrxiv.org/articles/preprint/Ligand_Rearrangement_Leads_to_Tetrahydrothiophene-Functionalized_N_S-Heterocyclic_Carbene_Palladium_II_Complexes/13633301