Hanh (Hannah) Nguyen is the newest undergraduate member of the Engle Lab and is joining us from down the street at UCSD. She is working with Tanner (G2) on carbonylation chemistry and wasted no time setting up some high throughput screening in Scripps Automated Synthesis Facility in her first week. Welcome Hanh!
After a productive summer in lab, Ziyang (Nick) heads back to USTC to start his junior year. Nick had a fun time exploring San Diego and was the star player at the Engle Lab summer beach outing volleyball game. We wish Nick good luck in his future chemistry and hope he’ll visit next year!
After a two-month stay in the Engle lab, Tian-Zhang departs San Diego today to return to Nankai University just in time to begin his junior year. Tian-Zhang deepened his knowledge of organometallic chemistry and catalysis, made many new friends, and had the opportunity to explore several fun locations up and down the West Coast. Thanks to De-Wei for great mentorship throughout the summer!
After a brief lab cleanup, the Engle group made the short trip up to the Del Mar Beach, for an afternoon of grilling, swimming, cards, volleyball, and relaxing. It was a great opportunity to celebrate the arrival of several new group members and the departure of Tian-Zhang, who completes his two-month internship next month. Thanks to the social team for organizing a great day!
Tianhua (Josh) UG4 started his 6 month internship working with Mingyu G3 and has already began making some chiral phosphine ligands. Josh is excited to learn about catalysis and trying In-n-out burger.
Roman M2 begins his visiting masters program from the Glorius Lab. Roman is looking forward to enjoying the last bit of summer here in San Diego and going to the beach.
Our collaboration with Pfizer describing a γ-selective hydroarylation of alkenyl carbonyl compounds using arylboronic acid coupling partners was accepted for publication today in Chem. Sci. (click here). With this discovery for the first time we are able to use ubiquitous aryl boronic acids to install essentially any aryl group at will as the nucleophilic component in catalytic directed alkene 1,2-functionalization. Though the reaction mechanism was not a major focus at the time of our initial submission, we were encouraged by reviewers to think more about the details of this system (particularly our preliminary deuterium-incorporation experiments), and this ended up leading us along a fruitful line of inquiry that included Reaction Progress Kinetic Analysis (RPKA). This was an awesome team effort that involved critical contributions from members of our lab (Rei, Tanner, Kin, and Rohan), the Blackmond lab (David), and Pfizer (Gary, Shouliang, Mingying, Fen, and Indra). Special kudos to our high school co-author Rohan from High Tech High International, who was an intern in the lab earlier this year. In case anyone missed it, a pre-print of this work was published on ChemRxiv back in April (click here).
Congratulations to G4 student Joseph Derosa, who has been selected for the prestigious 2018/2019 Turner B. and Lesly Shelton award from the Skaggs Graduate School at Scripps Research. Well done and well deserved, Joe!
About the award: Mrs. Lesly Starr Shelton was among the most ardent supporters of Scripps Research. Mrs. Shelton, alongside her husband Turner, supported both undergraduate and graduate education at several insitutions across the US, but Scripps Research was perhaps closest aligned with her personal passions. Mrs. Shelton’s family had been involved in the early pharmaceutical industry and she knew firsthand the value of education in basic research and its application towards the diagnosis, prevention and treatment of disease. The Skaggs Graduate Schools continues to honor Mrs. Shelton’s legacy and passion for education and research each year by awarding the Turner B. and Lesly Shelton Scholarship to a promising young scientist at Scripps Research.