ORGANOMETALLICS (CHEM 530) 2021
• Syllabus
• Full playlist of lectures on YouTube

DAY 1: Strong Inference + Main Group Organometallics
• Worksheet • Lecture Video A • Lecture Video B • Handout
DAY 2: Organotransition Metal Complexes: History, Structure, and Bonding I
• Worksheet • Lecture Video A • Lecture Video B • Handout
DAY 3: Organotransition Metal Complexes: History, Structure, and Bonding II
• Worksheet • Lecture Video • Handout 1 • Handout 2
DAY 4: Elementary Reactions I
• Worksheet • Lecture Video
DAY 5: Elementary Reactions II
• Worksheet • Lecture Video
DAY 6: Elementary Reactions III
• Worksheet • Lecture Video
DAY 7: Carbenes and Other M–C and M–X Multiple Bonds
• Worksheet • Lecture Video
DAY 8: Principles of Catalysis and Ancillary Ligand Design
• Worksheet • Lecture Video
DAY 9: Catalytic Hydrogenation
• Worksheet • Lecture Video • Handout 1 • Handout 2
DAY 10: GUEST – Catalytic Cycloadditions (V. Schmidt, UCSD)
• Lecture Video
DAY 11: Catalytic Carbonylation
• Worksheet • Lecture Video
DAY 12: MIDTERM
DAY 13: Wacker- and Heck-Type Alkene Addition
• Worksheet • Lecture Video • Handout
DAY 14: Allylic Substitution
• Worksheet • Lecture Video • Handout
DAY 15: Olefin Metathesis
• Worksheet • Lecture Video • Handout 1 • Handout 2
DAY 16: Catalytic Cross-Coupling
• Worksheet • Lecture Video • Handout
DAY 17: GUEST – Interfacing Radicals and Cross-Coupling (T. Diao, NYU)
DAY 18: C–H Activation
• Worksheet • Lecture Video
DAY 19: GUEST – Application, Mechanism, and Catalyst Activation in the Real World (S. Wisniewski/R. Green, BMS)
DAY 20: GUEST – Natural and Artificial Metalloenzymes (H. Renata, Scripps-FL)
• Slides • Lecture Video
DAY 21: Wikipedia Page Presentations
DAY 22: GUEST – Innovations in Discovery Process Chemistry (E. Edelstein/T. Lyons/E. Corcoran, Merck)
DAY 23: GUEST – Frontiers in Catalysis with p-Block Elements (J. Cornella, MPI)
DAY 24: FINAL EXAM

2021 Problem Sets, Midterm, and Final (Grading Keys Available Upon Request)
• Problem Set 1
• Problem Set 2
• Midterm
• Final

Wikipedia Project
Since 2017, the Scripps Organometallics class created >50 new Wikipedia pages on topics relevant to coordination chemistry, organometallics, and catalysis. Below are representative articles voted among the best by the class for each year:

2021
• Concerted Metalation Deprotonation
• Crystal Sponge
• Conia-Ene Reaction
• Organotechnicium Compound
• Metal–Ligand Cooperativity
• Shuttle Catalysis

2019
• Artificial Metalloenzymes
• Cross Electrophile Coupling
• Philippe Barbier
• Metallo-Ene Reaction
• Beta-Carbon Elimination

2017
• Activation of Cyclopropanes by Transition Metals
• Mukaiyama Hydration
• Spin Forbidden Reactions
• Tsuji–Wilkinson Decarbonylation Reaction
• Ugi’s Amine