Bridges Program Visits TSRI

For the second year running, TSRI hosted a group of students and educators from the North San Diego County Bridges to the Future Program, an NIH-sponsored collaborative program among CSU San Marcos, Palomar College, and MiraCosta College. The goal of the program is to prepare students from underrepresented ethnic and racial groups at community colleges for seamless transition to four-year colleges. Keary kicked off the half-day visit with an overview of research in the Engle lab. Students then participated in a series of lab tours and hands-on activities with the Ward, Lamia, Romesberg, Sharpless, and Engle labs.

N-Alkylation of 2-Pyridones with Alkenes

In a manuscript appearing online today in Tetrahedron, John, Van, and Miranda report a new method to effect intermolecular N-alkylation of 2-pyridones using an alkene as the alkylating reagent. The reaction employs a directed nucleopalladation/protodepalladation strategy and functions with a range of 2-pyridones and related aza-heterocycles. Special congratulations to our undergraduate co-author, Miranda, who also just completed her undergraduate degree at UCSD! The manuscript is part of a special issue celebrating Prof. Ang Li’s 2017 Tetrahedron Young Investigator Award. Click here for a link to the manuscript. Way to go, team!


IMG_2549(not pictured: Miranda)