Directed 1,2-Dialkylation of Alkenes – Now In Press

Our paper describing directed 1,2-dialkylation of alkenyl carbonyl compounds via nickel catalysis is now online in Chem. Sci. This work represents the first method for controlled introduction of differentiated alkyl groups onto an non-conjugated alkene and offers exciting potential for generating densely functionalized products with high-sp3 content in a rapid manner. Congrats to the authors, Joe, Vincent, Van, and Mingyu! Special shout out to undergraduate co-author and TSRI-SURF program alum Vincent. Click here for a link to the paper. A pre-print of this work was published on ChemRxiv back in January (click here).

dialkylation