Borylative Alkene 1,2-Difunctionalization Methodology Now Online

In a paper appearing today in the Just Accepted section of J. Am. Chem. Soc., we describe new methodology to carry out directed, borylative 1,2-difunctionalization of alkenes with various carbon/nitrogen nucleophiles and B2pin2 as the reaction partners. Notably, the reaction works with substrates containing an alkene that is distal from the directing group via a 6-membered palladacycle intermediate. Congrats to the authors, Zhen, Hui-Qi, and May! And special props to undergrad co-authors Hui-Qui and May! Click here for a link to the paper.


20180207_195852(not pictured: Hui-Qi)