Catalytic syn-Carbosulfenylation Paper Published in J. Am. Chem. Soc.

The final version of our paper describing Ni(I)/Ni(III)-catalyzed carbosulfenylation is online today in the Journal of the American Chemical Society. The method allows conversion of a diverse collection of widely available alkenes bearing native directing groups to structurally complex organosulfide products, with reactivity and selectivity emanating from specially tailored N–S electrophiles. The syn-stereoselectivity of the reaction complements classical thiiranium chemistry, which delivers anti-sulfenylfunctionalized products. Congrats to graduate students Zi-Qi and Taeho and former SURF intern Yilin. Great work!

For a link to the paper in J. Am. Chem. Soc., click here:

As a reminder, a pre-print of the paper was first deposited back in December 2021: