Today in a pre-print on ChemRxiv, we describe a highly unique cascade hydrofunctionalization process mediated by a chiral CuH catalyst. This multicomponent reaction transforms terminal alkynes into enantioenriched 1,1-aminoboronates in a single step, streamlining access to this emerging class of pharmacophores. We present preliminary experimental and computational data that sheds light on the reaction mechanism and origins of selectivity. Congrats to all of the authors from the Engle lab (De-Wei, Yang, Tian-Zhang, and Xin, Automated Synthesis Facility (Jason and Brittany), and Liu lab at Pittsburgh (Huiling)! Click here for a link to the paper.